Cytotoxic Sesquiterpenoids From Soft Soral Capnella imbricata
نویسندگان
چکیده
منابع مشابه
New cytotoxic sesquiterpenoids from Siegesbeckia glabrescens.
Two new sesquiterpenoids, siegenolides A (1) and B (2), and two known sesquiterpenes 3 and 4 were isolated from Siegesbeckia glabrescens. Their structures were elucidated by spectroscopic analyses, and they were further evaluated for their cytotoxic activities against human cancer cells (MCF-7, AsPC-1, SW480, HCT 116, HepG2, HeLa). Compounds 1-4 showed differential cytotoxic effects on the targ...
متن کاملCytotoxic beta-dihydroagarofuran sesquiterpenoids from the fruits of Celastrus orbiculatus.
Assay-guided fractionation led to the isolation of nine beta-dihydroagarofuran sesquiterpenoids from the fruits of Celastrus orbiculatus. All isolated beta-dihydroagarofuran sesquiterpenoids were tested for their cytotoxic activity against human melanoma A375-S2 and human cervical carcinoma Hela cell lines. Among them, compounds 1-5 and 7 showed cytotoxic activity. Compound 3 exhibited promisin...
متن کاملOxygenated Ylangene-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis
Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1-3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectroscopic data. Compound 1 was shown to exhibit cytotoxicity against HepG2, MDA-MB231 and A549 cancer c...
متن کاملNardosinane-Type Sesquiterpenoids from the Formosan Soft Coral Paralemnalia thyrsoides
Five new nardosinane-type sesquiterpenoids, paralemnolins Q-U (1-5), along with three known compounds (6-8), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configuration of 1 was determined by the application of Mosher's method on 1. Among these metabolites, 1...
متن کاملNardosinane sesquiterpenoids from the Formosan soft coral Lemnalia flava.
Four new nardosinane-type sesquiterpenoids, flavalins A-D (1-4), have been isolated from the Formosan soft coral Lemnalia flava. The structures of the new metabolites were determined by extensive spectroscopic analysis, and the structure of 2 was confirmed by X-ray diffraction analysis. A plausible biosynthetic pathway to 1 and 2 is proposed. Compound 1 was found to display dose-dependent inhib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2019
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x19857494